S 545 United States Senate · 119th Congress

Combating Illicit Xylazine Act

The Combating Illicit Xylazine Act places xylazine - a veterinary sedative increasingly found in illicit drug mixtures - into Schedule III of the Controlled Substances Act, subjecting it to federal regulation as a controlled substance. It specifically allows veterinary use without requiring registration of the ultimate user (e.g., pet owners or veterinarians) if xylazine is dispensed by a registered veterinarian or pharmacy with a vet prescription and used for animals owned by the user, under their care, or in authorized animal programs. The bill provides a one-year delay for labeling and packaging requirements and a 60-day delay for registration and recordkeeping for veterinary use to ease implementation. Additionally, it adds xylazine to the Arcos tracking system for controlled substances and mandates two congressional reports on illicit use prevalence within 18 months and 4 years of enactment.
Bill status in committee 1 of 4 stages cleared
Introduction
Feb 2025
Committee Review
Floor Vote
President
Introduced Feb 12, 2025 Last action Apr 15, 2026
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Full legislative history

Actions timeline

Total actions
5
Key actions
2
Committee
3
Apr 15, 2026
Upper · Passed
Committee on the Judiciary. Reported by Senator Grassley with an amendment in the nature of a substitute. Without written report.
upper
Mar 26, 2026
Upper · Passed
Committee on the Judiciary. Ordered to be reported with an amendment in the nature of a substitute favorably.
upper
Feb 12, 2025
Committee
Read twice and referred to the Committee on the Judiciary.
upper
Feb 12, 2025
Introduced
Introduced in Senate
upper
1 primary · 35 co-sponsors

Sponsors