Fairness in Fentanyl Sentencing Act of 2025

This bill reduces sentencing thresholds for fentanyl and similar synthetic opioid offenses by lowering the quantity amounts that trigger mandatory minimum penalties (e.g., changing "400 grams" to "20 grams" for certain offenses). It requires the U.S. Sentencing Commission to update federal sentencing guidelines within 120 days to align with these changes. Additionally, it authorizes $9 million for the U.S. Postal Service to purchase chemical screening devices and staff to detect fentanyl and other synthetic opioids in mail and packages. The bill directly affects individuals convicted of federal drug offenses under the Controlled Substances Act.