SIMSA Act of 2025

The SIMSA Act of 2025 creates a new Schedule A for controlled substances under federal drug law. It defines Schedule A substances as those imported into the U.S. with chemical structures substantially similar to existing Schedule I-V substances and having similar effects on the central nervous system. The bill establishes procedures for the Attorney General to temporarily schedule substances for up to 5 years (with possible 180-day extensions), requiring consultation with the Secretary of Health and Human Services before permanent scheduling. It increases penalties for violations involving Schedule A substances, including prison terms up to 30 years for repeat offenses and higher fines, and requires specific labeling with IUPAC nomenclature for these substances.