Maternal and Infant Syphilis Prevention Act

This bill requires the Secretary of Health and Human Services to issue guidance to state Medicaid programs, CHIPs, and Indian health programs within 12 months of enactment. The guidance focuses on improving syphilis screening for pregnant women (including third trimester and delivery testing), expanding treatment access, educating medical providers and patients, and integrating telehealth services. It directly affects states administering Medicaid/CHIP programs, Indian Health Service, tribes, and urban Indian health organizations by setting best practices for preventing congenital syphilis. The bill mandates a report to Congress within two years analyzing how states implement these guidance recommendations.