Expressing support for the designation of May 5, 2025, as the "National Day of Awareness for Missing and Murdered Indigenous Women and Girls".

HRES 381 designates May 5, 2025, as the "National Day of Awareness for Missing and Murdered Indigenous Women and Girls," calling for public commemoration of victims and solidarity with their families. The resolution urges the public and groups to honor both documented and undocumented cases while recommending the Department of Justice commission a new study on the crisis, citing that the last major study was published in 2016. It does not create new laws or funding but aims to raise awareness about ongoing issues, referencing recent data showing 5,614 Indigenous women and girls reported missing in 2024. This symbolic resolution directly affects Indigenous communities, families, and the public, aligning with prior federal efforts like Savanna’s Act and the Not Invisible Act.