To amend the Intermodal Surface Transportation Efficiency Act of 1991 to designate a portion of United States Route 74 in North Carolina as a future interstate, and for other purposes.

HR 1333 designates a specific segment of U.S. Route 74 in North Carolina - from Columbus to Kings Mountain - as a future interstate highway under the Intermodal Surface Transportation Efficiency Act of 1991. This bill updates existing transportation law to add this corridor to the list of high-priority routes and future interstate designations. The change directly affects communities along this North Carolina stretch by formally recognizing it for potential future interstate development, though it does not allocate funding or initiate construction. The bill is procedural, focusing solely on legislative designation within federal transportation planning.