An Act amending the act of April 14, 1972 (P.L.233, No.64), known as The Controlled Substance, Drug, Device and Cosmetic Act, further providing for drug overdose medication.

HB 2181 amends Pennsylvania's Controlled Substance Act to define "opioid antagonist" as drugs approved by the U.S. Food and Drug Administration for emergency reversal of opioid overdoses, including naloxone hydrochloride and similar FDA-approved medications. The bill specifically adds these examples to the legal definition within the existing law. This change directly affects healthcare providers, emergency responders, and pharmacists who administer these medications during opioid overdose emergencies by clarifying the legal scope of approved treatments.