S 5303 New York Senate · 2025 Regular Session

Enacts the medical psilocybin act

This bill, known as the Medical Psilocybin Act, would create a regulated program allowing the use of psilocybin, a compound found in certain mushrooms, to treat specific medical conditions. It directly affects qualified patients diagnosed with issues such as treatment-resistant depression, post-traumatic stress disorder, substance use disorders, end-of-life care, or cluster headaches, as well as healthcare providers and businesses that produce or administer the substance. The legislation establishes a framework where licensed producers grow and prepare the medication, while licensed healthcare providers or trained supervisors determine appropriate dosing and oversee its administration in safe settings. Key provisions include creating a registry for patients and caregivers, setting strict safety and testing requirements for products, and providing exemptions from criminal penalties for the legal medical use and possession of psilocybin. The bill also mandates that the Department of Health develop detailed rules for licensing, training, recordkeeping, and monitoring to ensure the program operates safely and effectively.
Bill status in committee 1 of 4 stages cleared
Introduction
Feb 2025
Committee Review
Floor Vote
Governor
Introduced Feb 20, 2025 Last action May 8, 2026
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What changed between versions

S5303 S5303A · 5 edits
MODERATE
The bill was significantly rewritten to shift from a regulated adult-use model to a strict medical-only program. It now requires psilocybin to be used only by patients with specific conditions like depression or PTSD under the supervision of licensed healthcare providers, eliminating provisions for general adult access and commercial cultivation.
Scope change
The bill's scope changed from allowing both adult recreational use and medical use to authorizing psilocybin solely for treating qualified medical conditions.
SCOPE

Provisions establishing a framework for regulated adult use of psilocybin and commercial cultivation licenses were removed.

ELIGIBILITY

A new list of qualifying medical conditions was added, including major treatment-resistant depression, PTSD, and substance use disorders.

DEFINITION

The definition of a 'licensed healthcare provider' was narrowed to require a physician, psychologist, or nurse practitioner who has completed specific training, replacing a broader list of wellness professionals.

REQUIREMENT

New requirements were added for a 'medical use of psilocybin program' within the Department of Health, including procedures for licensing producers and patients.

The bill now explicitly requires psilocybin administration to be supervised by a licensed healthcare provider or a qualified supervisor.

Floor votes

How they voted

No floor votes recorded yet.
Full legislative history

Actions timeline

Total actions
4
Key actions
2
Committee
2
Amendments
2
May 8, 2026
Upper · Passed
PRINT NUMBER 5303A
upper
May 8, 2026
Upper · Passed
AMEND (T) AND RECOMMIT TO HEALTH
upper
Jan 7, 2026
Committee
REFERRED TO HEALTH
upper
Feb 20, 2025
Committee
REFERRED TO HEALTH
upper
1 primary · 5 co-sponsors

Sponsors