Prohibits pharmacy benefits managers from operating pharmacy practice sites directly or indirectly.

S 3381 prohibits pharmacy benefits managers (PBMs) from owning or operating pharmacies directly or indirectly in New Jersey. The law requires PBMs to divest existing pharmacy ownership by July 2027, aiming to prevent conflicts where PBMs set drug prices while also running pharmacies. This affects PBMs with pharmacy holdings and aims to increase competition for patients by reducing anticompetitive practices that limit pharmacy choices and may raise drug costs. The bill focuses on structural changes to the pharmacy market, not on specific drug pricing outcomes.