Modifies provisions relating to advanced practice registered nurses

HB 2391 modifies Missouri law to expand prescribing authority for advanced practice registered nurses (APNs). It allows APNs with a board-certified controlled substance prescriptive authority to prescribe medications in Schedules III, IV, and V, and limited Schedule II (specifically hydrocodone for hospice patients). The bill requires APNs to either work under a collaborative practice agreement with a physician or qualify for an exemption from that requirement. It also prohibits APNs from prescribing controlled substances for themselves or family members and limits Schedule II/hydrocodone prescriptions to 120-hour supplies without refills. This directly affects APNs seeking greater prescribing independence within defined boundaries.