A bill for an act relating to the controlled substance crystalline polymorph psilocybin.

HF 383 would remove the pharmaceutical form of psilocybin (specifically crystalline polymorph COMP 360) from Iowa's Schedule I controlled substances list once the U.S. Food and Drug Administration (FDA) approves it and reschedules it under federal law. This would allow doctors to legally prescribe, distribute, and market COMP 360 for medical use, directly affecting healthcare providers and patients seeking this treatment. The bill automatically aligns Iowa law with federal FDA decisions on this specific pharmaceutical formulation. Note: The bill was vetoed by the governor on June 11, 2025, so it has not become law.